[σκόλοψ] perhaps from the base of G4628 and G3700; withered at the front, i.e. a point or prickle (figuratively, a bodily annoyance or disability)
Usages throughout the bible
2 Corinthians 12:7
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And lest I should be exalted above measure through the abundance of the revelations, there was given to me a thorn G4647 in the flesh, the messenger of Satan to buffet me, lest I should be exalted above measure.