from H2015; an upset, i.e. (abstract) perversity; turning of things upside down.
Usages throughout the bible
Isaiah 29:16
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Surely your turning of things upside down H2017 shall be esteemed as the potter's clay: for shall the work say of him that made it, He made me not? or shall the thing framed say of him that framed it, He had no understanding?